Uroporphyrin (octacarboxyl porphyrin) 8
Heptacarboxyl porphyrin 7
Hexacarboxyl porphyrin 6
Pentacarboxyl porphyrin 5
Coproporphyrin (tetracarboxyl porphyrin) 4
Harderoporphyrin (tricarboxyl porphyrin) 3
Protoporphyrin (dicarboxyl porphyrin) 2
Coproporphyrin predominates in normal urine. An increase in total urine porphyrins with a predominance of coproporphyrin is seen especially in HCP and VP. But this finding alone is very nonspecific, because increases in urine porphyrins and especially coproporphyrin are common in many medical conditions such as liver diseases, bone marrow disorders and lead poisoning. Therefore, increases in urine coproporphyrin are often not due to Porphyria.
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